Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19

Abstract

The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a serious public health threat worldwide with millions of people at risk in a growing number of countries. Though there are no clinically approved antiviral drugs and vaccines for COVID-19, attempts are ongoing for clinical trials of several known antiviral drugs, their combination, and the development of vaccines in patients with confirmed COVID-19. This review focuses on the latest approaches to diagnostics and therapy of COVID-19. We have summarized recent progress on conventional therapeutics such as antiviral drugs, vaccines, anti-SARS-CoV-2 antibody treatments, and convalescent plasma therapy which are currently under extensive research and clinical trials for the treatment of COVID-19. The developments of nanoparticle-based therapeutic and diagnostic approaches have been also discussed for COVID-19. We have assessed recent literature data on this topic and made a summary of current development and future perspectives.

Keywords: ARDS; anti-SARS-CoV-2 antibody; antiviral drugs; antiviral vaccines; convalescent plasma therapy; immunotherapy; nanotherapeutics.

One Comment

  1. Hence Covid 19 is respiratory disease the disease must be deadly and an easely kill, the virus in one of the the world non deadly diseases in the world, virus can multiplies in very small period of time to produce vast varieties of its on kind.
    Hence the disease is new we have a very little knowledge of Covid 19, and the severe accute respiratory syndrome know as Covid 19 kills rapidly.

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